Influence of Poly-L-Lactic Acid to Gelatin Scaffold for Tissue Engineering Applications
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Abstract
This research was aimed to investigate the influences of poly-L-lactic acid on gelatin scaffold. The gelatin scaffold was fabricated via freeze drying technique and blended with poly-L-lactic acid in different ratios. The surface structure of gelatin/poly-L-lactic acid scaffolds in different conditions was investigated by using Scanning Electron Microscopy (SEM). The poly-L-lactic acid blended on gelatin scaffold demonstrated the molecular structure of poly-L-lactic acid aggregated on gelatin scaffold with decreasing of mean pore size of scaffold structure when increasing of poly-L-lactic acid contentin some ratio. The results from swelling test revealed that increasing of poly-L-lactic acid content increased in swelling ratio of gelatin scaffold with significant different when compared with pure gelatin scaffold. These results proved that using poly-L-lactic acid blended with gelatin scaffold changed in morphology of gelatin scaffold and improved its physical properties of the gelatin scaffold with enhanced in swelling properties of gelatin scaffolds which could be applied using in tissue engineering applications.
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