THE STUDY OF THE ABNORMAL IMMUNOGLOBULIN TYPES RELATED TO DISEASE AND FREQUENCY OF EXAMINATION IN PATIENTS AT SRINAGARIND HOSPITAL, FACULTY OF MEDICINE, KHON KAEN UNIVERSITY, THAILAND

Abstract

The study of the abnormal immunoglobulin types related to disease and frequency of examination in patients at Srinagarind Hospital, Faculty of Medicine, Khon Kaen University, Thailand aimed to study Multiple Myeloma (MM.) of patients with hematological cancer caused by abnormalities in plasma cells which is a group of white blood cells. In Multiple Myeloma patients, plasma cells grow abnormally. Resulting in abnormalities in the body. Most of them are created and detected abnormal immunoglobulins, which can be distinguished and confirmed with an Immunofixation Test (IFE.), while at the same time IFE is not a test. For screening, it's just a test to confirm the type of disease. In smaller hospitals, tests of this nature may not be available to support the service. However, the fee for IFE. examination in the Comptroller General's Department system is charged up to 3,000 baht per time, so the results of the IFE. study are suitable for examination to confirm the type of disease and should be tested no more than 2 times a year due to the form of immunoglobulin often does not change. For patients with Nephrotic Syndrome, an IFE. test once a year is considered appropriate since MM. patients are often predisposed to impaired renal function. The study also found that in patients with no non specific diagnosis, IFE. was tested, possibly because the doctor wanted to determine or exclude the diagnosis to rule out the risk of MM. At the same time, SPEP was used to monitor patients. It can help a lot. And the price is very different from IFE examination, where SPEP costs 300 baht per time, and especially in the MM. group, it was found that the SPEP results can be evaluated by up to 95.8% of patients. Keywords: Multiple Myeloma (MM.) , Immunofixation Test (IFE.)