Histamine Receptors and Their Ligands

Ruengwit Kitbunnadaj

Authors

Ruengwit Kitbunnadaj Department of Pharmaceutical Chemistry and Pharmacognosy, Faculty of Pharmaceutical Sciences, Naresuan University,Phitsanulok 65000, Thailand.

Abstract

Histamine, a biogenic amine, mediates multiple physiological effects through binding to its receptors, i.e., H₁, H₂, H₃, and H₄ receptors. Currently, the histamine receptors have taken attention as important targets for the treatment of several diseases and disorders. In this article, a short review about histamine, histamine receptors, and histamine receptor ligands is described in the state of art in molecular biology, pharmacology, and medicinal chemistry.

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