Antioxidant Activities and Electrochemical Behaviors of Xanthones from Cratoxylum cochinchinense and Cratoxylum formasum

Benjamat Chailap; Thanesuan Nuanyai

doi:10.14456/nujst.2019.24

Authors

Benjamat Chailap General Education Department, Faculty of Liberal Arts, Rajamangala University of Technology Rattanakosin
Thanesuan Nuanyai Faculty of Liberal Arts,Rajamangala University of Technology RattanakosinWang Klai Kangwon Campus

DOI:

https://doi.org/10.14456/nujst.2019.24

Keywords:

Xanthone, Cratoxylum cochinchinense, Cratoxylum formasum, Antioxidant, Electrochemical

Abstract

Seven xanthones; dulcisxanthone B (1), ß-mangostin (2), 1,3,7-trihydroxy-2,4-di-(3-methylbut-2-eyl)-xanthone (3), cudratricusxanthone E (4), cochinchinone A (5), 2-geranyl-1,3,7-trihydroxy-4-(3,3-dimethylallyl)-xanthone (6), and cochinchinone B (7) were isolated from twigs of Cratoxylum cochinchinense and Cratoxylum formasum. The structures of all isolated compounds were elucidated by spectroscopic methods (¹H, ¹³C, ¹H-¹H COSY, ¹H-¹³C HSQC, and ¹H-¹³C HMBC) and compared with previous literatures. All compounds were evaluated in vitro for antioxidant activity using DPPH assay. Their electrochemical behaviors were investigated by cyclic voltammetry. The results derived from two techniques were consistent. Compounds 1, 2, 4 and 7 exhibited strong antioxidant activities. Considering the structure-activity relationship, the hydroxy group at C-6 played an important role to antioxidant power.

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